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HiLo is a clinical research study on how best to manage blood phosphate levels in patients on dialysis.
Researchers will compare how participants feel, how often they are hospitalized, and how long they live based on the level of phosphate in their blood.
Current guidelines for managing blood phosphate levels are based on expert opinion, not from results of clinical research.
For years, doctors have thought that patients on dialysis would feel and do better if their blood phosphate level was lowered. However, this has never been studied in a formal clinical research study until now in HiLo.
Researchers from the Duke Clinical Research Institute will coordinate the operations and data functions of the study. The study will take place in outpatient dialysis centers that care for a substantial number of the U.
The HiLo study team consists of nephrologists, dietitians, facility managers, scientists, and clinical research professionals.
The variable speed pulley is normally mounted on the moveable shaft and a fixed diameter sheave on the stationary shaft. By using an adjustable motor base, speed variation of the driven shaft is accomplished by mechanically changing the center distance between the shafts.
An increase in center distance will pull the belt to a smaller diameter in the variable speed pulley.
This increases the drive ratio and reduces the driven shaft RPM. A decrease in center distance allows the spring-loaded pulley faces to close and push the belt to a larger diameter.
They have single face movement to provide greater economy on longer center distance V-V drives where absolute belt alignment is not critical.
Their through bore construction allows mounting from either end. Two Face Movable Design for standard V-belts Maintains belt alignment between the variable speed pulley and the companion sheave.
This is an important feature with close center distance drives. Models and are an exception, however, and should use recommended shaft center distances.
In a relational database management system this could be through a stored procedure. Example implementation in Python. Mentioned in the book NHibernate 4.
Mentioned in the book ASP. NET Core 2 Fundamentals on page Algorithm uses a high value retrieved from database and combines it with range of low values to generate a unique identifier.
But you can override this to use a different table. One is hi which is sourced from a database table and other is lo which is calculated by NHibernate.
NHibernate combines these two numbers using a formula to generate a unique number that can be used as identifier. While auto incremented IDs are simpler, whenever you add an entity to the context, this addition forces the entity to be inserted to the database.
That is because we can only retrieve the ID if the actual insertion happens in the case of auto incremented IDs.
The HiLo algorithm frees us from this restriction by reserving the IDs beforehand using a database sequence.
Had support since at least version 3. Supported by Marten  persistence library for.